Dynamic Brain Maps: Mapping Brain Changes in Schizophrenia

These animations show a spreading wave of gray matter loss, in adults with schizophrenia, during a 1-year period following the first episode of psychosis. Different trajectories are shown for patients treated with haloperidol and for patients treated with olanzapine. Changes are not uniform over time, and are measured from MRI scans collected 0, 3, 6 and 12 months after the onset of psychotic symptoms. Click on each image to play the movies [animated GIF format, 13MB].

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Contact Information

  • Mail:

    Paul Thompson, Ph.D. thompson@loni.ucla.edu
    Associate Professor of Neurology
    UCLA Lab of Neuro-Imaging and Brain Mapping Division
    Dept. Neurology and Brain Research Institute
    635 Charles Young Drive, NRB 225E
    UCLA School of Medicine
    Westwood, Los Angeles CA 90095-1769, USA.

  • E-mail: thompson@loni.ucla.edu
  • Tel: (310)206-2101
  • Fax: (310)206-5518